- A clinical diagnosis of vitiligo is rendered
- Recommend narrow-band ultraviolet B (NB UVB) phototherapy
combined with topical corticosteroid ointment applied b.i.d
- Follow-up in three months
Follow-up evaluation strategy
Three-month follow-up evaluation
- Subtle repigmentation, with areas of follicular accentuation of
newly pigmented areas
- Recommend continuing NB UVB phototherapy and topical steroid
Six-month follow-up evaluation
- Approximately 60% repigmentation noted
- Continue phototherapy and topical steroid treatment with
follow-up evaluation at three-month intervals
Vitiligo is a common disorder of depigmentation that is marked
by the histologic loss of epidermal melanocytes. It may occur in
patterns: localized, segmental, generalized, or a variant with
acral predilection and periorificial involvement. Vitiligo may be
associated with autoimmune disease.
The duration of vitiligo is lifelong and its disease course may be
difficult to predict. The mainstay of treatment includes topical
corticosteroid and calcineurin therapies, and narrow-band
ultraviolet phototherapy; combined therapy may be most effective
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comprehensive overview, Part I. JAAD. 2011;65(3):473-491.
Felsten LM, Alikhan Al, Petronic-Rosic V. Vitiligo: a
comprehensive overview, Part II. JAAD. 2011;65(3):493-514.
Taieb A, Picardo M. Vitiligo. N Engl J Med.
Whitten ME, Pinart M, Batchelor J, Lushey C, Leonardi-Bee J,
Gonzalez U. Interventions for vitiligo. Cochrane Database Syst Rev.