Answer: Seborrheic keratosis
Criteria for diagnosis
histopathologically: A symmetrical,
well-circumscribed epidermal neoplasm made up of interconnected
columns of "basaloid" and "squamoid" cells, the former containing
melanin, that contains infundibular tunnels with laminate and
basket-woven horn, is a seborrheic keratosis.
Differential diagnosis histopathologically:
There is none.
Criteria for diagnosis clinically: A
sharply demarcated, flat, brown papule with a papillated surface
that is located on the temple of an older person is consonant with
Differential diagnosis clinically: There is
Clinicopathologic correlation: The plaque
results from the thickening of the epidermis. The pigmentation is
due to an increase in melanin within the "basaloid" cells.
Options for therapy predicated on knowledge of
histopathologic findings: The lesion is benign and
therefore no therapy is needed.
1) Seborrheic keratosis is a benign epidermal neoplasm that
occurs in adults and is localized preferentially on the trunk, but
can develop on all parts of the body surface except the palms and
2) Attempts have been made to classify seborrheic keratosis into
different types, based partly on their appearance architectural,
partly on the predominating cell type. At present, six types have
been described: acanthotic, hyperkeratotic (verrucous),
reticulated, clonal, irritated, and melanoacanthoma.
3) If one examines critically seborrheic keratoses that have
been classified as acanthotic or hyperkeratotic, it turns out that
these classifications are not entirely justified because similar
architectural attributes can be encountered in both types.
Acanthosis, hyperkeratosis, and the formation "horn pseudocysts"
are findings histopathologic of seborrheic keratosis; each of these
characteristics can be more or less pronounced in an individual